My sister

We have been trying to contact my sister, Wako, via phone and email to no avail. I think we've been trying for about 2 weeks. She doesn't write or call us back.... My parents are driving me mad with their worries. This is not the first time it has happened. In fact, it's not the second time. But everytime they don't hear responses to numerous calls and email attempts, they worry. I am sure she has her reasons and maybe she doesn't think it's a big deal to delay responding. I am not sure. Has anyone been in touch with her physically or virtually?